Acute antipsychotic-induced akathisia revisited

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Acute antipsychotic-induced akathisia revisited.

Akathisia remains one of the most prevalent and distressful antipsychotic-induced adverse events. Effective and well-tolerated treatment is a major unmet need in akathisia that merits a search for new remedies. Accumulating evidence indicates that agents with marked serotonin-2A receptor antagonism may represent a new class of potential anti-akathisia treatment.

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The epidemiology of drug-induced akathisia: Part I. Acute akathisia.

This article reviews the epidemiological data on drug-induced acute akathisia, examining studies in which akathisia was the primary focus as well as those in which it was one of a number of drug side effects studied. The studies are diverse in methodology and suffer from many limitations. Incidence rates for acute akathisia with conventional neuroleptics vary from 8 to 76 percent, with 20 to 30...

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Revisiting Antipsychotic-induced Akathisia: Current Issues and Prospective Challenges

BACKGROUND Akathisia continues to be a significant challenge in current neurological and psychiatric practice. Prompt and accurate detection is often difficult and there is a lack of consensus concerning the neurobiological basis of akathisia. No definitive treatment has been established for akathisia despite numerous preclinical and clinical studies.] Method: We reviewed antipsychotic-induced ...

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Effect of Vitamin B6 versus Propranolol on Antipsychotic-Induced Akathisia: A pilot comparative double-blind study

Background: Akathisia is a common adverse effect of antipsychotic drugs and is characterized by subjective feelings of restlessness. First-line treatment usually consists of propranolol, a beta adrenergic antagonist. However, propranolol does not seem to be efficacious in up to 70% of patients. This study was aimed to evaluate the effect of vitamin B6 versus propranolol on antipsychotic-induced...

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Effect of Vitamin B6 versus Propranolol on Antipsychotic-Induced Akathisia: A pilot comparative double-blind study

Background: Akathisia is a common adverse effect of antipsychotic drugs and is characterized by subjective feelings of restlessness. First-line treatment usually consists of propranolol, a beta adrenergic antagonist. However, propranolol does not seem to be efficacious in up to 70% of patients. This study was aimed to evaluate the effect of vitamin B6 versus propranolol on antipsychotic-induced...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 2010

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.bp.109.070540